Program
NEW (Last update 30 June 2025)
General information:
- All contributions and sponsor exhibition will be in "Aula Mediterraneo".
- Plenary lectures, PL, are 30 minutes + 10 minutes Q/A.
- Invited talks, IT, are 20 minutes + 5 minutes Q/A.
- Sponsor talks, ST, are 10 minutes, no Q/A.
- Oral communications, O, are 10 minutes + 2 minutes Q/A.
- Oral S. communications, OS, are 5 minutes, no Q/A.
- Poster sessions, P, occur during lunches.
- All information about type of contribution is available on the website in "Information".
Monday, June 23rd
8:00 Registrations
9:00 Workshop, Francesca Rita Novara - Wiley "Adapting your paper to a rapidly changing publication landscape"
9:40 Opening
10:00 Plenary Lecture, PL1
Chairperson: TBD
Gianvito Vilè - Polytechnic of Milan
"Green-by-Design Synthesis of Small-Molecule APIs via Atomically Precise Catalyst Design"
10:50 Session 1, Biomaterials
Chairperson: TBD
O1 Andrea Magrì, University of Catania
"Amyloid-b oligomers rewire VDAC1 electrophysiology and affect mitochondrial respiration in Alzheimer's disease"
O2 Claudia Pigliacelli - Polytechnic of Milan
"Self-assembly of short peptides towards functional nanomaterials"
O3 Sergio Scirè - University of Palermo
"PCI, a smart electrospun nano fibrillar biomaterial with magnetic, photothermal, and non-adhesive features for biomedical use"
O4 Giulia Turrin - University of Ferrara
"Enhancing biocompatibility of polyimide through surface covalent binding of dexamethasone for neural implantable devices"
O5 Giorgia Giovannini - Mario Negri Institute
"Design of bio-responsive nanomaterials as controllable carriers and diagnostic tools"
O6 Adriana Carolina Torres Mansilla - Institute of Science, Technology and Sustainability for Ceramics
"Bioinspired nanocrystalline surfaces for bone infection treatment: exploring the osteoinductive and optimized properties of antibacterial nanostructures"
12:20 Sponsor talk, ST1
Alice Pedruzzi - Buchi
"Title TBD"
12:35 Session 1s, Multimolecules
Chairperson: TBD
OS1 Lourdes Rivas - Barcelona Institute for Global Health
"An aptamer-based rapid diagnostic test for the simultaneous detection of malaria and dengue"
OS2 Silvia Orecchio - University of Palermo
"Mitigation of environmental toxicity in perovskite solar panels through perfluoroalkylated additives"
OS3 Cristian Reale - University of Messina
"A fast separation method for coumarin and furocoumarins quantification in perfumes by means of supercritical fluid chromatography"
OS4 Alessia Bono - University of Palermo
"Synthesis, in vitro exploration, and reactivity studies of 6-chloropyridin-2-yl benzoates as promising covalent fragments with antiviral and pro-apoptotic activities"
OS5 Elisabetta Rosa - University of Naples Federico II
"Stimuli-responsive hydrogels from low-complexity peptide domains"
OS6 Sara Amata - University of Palermo
"Synthesis and SAR of 1,2,4-oxadiazole derivates as potential antibacterial agents"
OS7 Miryam Perrucci - University of Teramo
"Newest approach for micro- extraction from complex matrix"
OS8 Federico Magrin - University of Padua
"Lead optimization of specific OPA1 inhibitors enhancing cytochrome c release and cell death"
OS9 Ignazio Fiduccia - University of Palermo
"Proteomic insights into LRBA deficiency: investigating oxadiazole-based readthrough therapy"
13:40 Poster session 1, P1 + Lunch
14:30 Session 2, Prediction
Chairs: TBD
O7 Cinzia Franchin - University of Padua
"Strategies and technological approaches to reveal proteins in traces from plasma samples"
O8 Lisa Rita Magnaghi - University of Pavia
"A statistical approach towards biofilms hydrophilicity characterization integrating ANOVA, DOE, and PCA"
O9 Adriana Coricello - University of Urbino
"An ABMD-based workflow for predicting relative residence times of ligands against systems of pharmacological interest"
15:15 Session 2s, Nanomaterials
Chairperson: TBD
OS10 Maria Ruggirello - University of Siena
"Development of Nanobody Drug Conjugates (NbDCs) using SARS-CoV-2 as a model for targeted antiviral therapy"
OS11 Rossella Infantino - University of Palermo
"Highly functionalized hybrid carbon nano-forms materials for photodegradation of pollutants from water"
OS12 Annalisa Morelli - Mario Negri Institute
"Lung disorders treatment: Investigating the impact of a nasal nanoformulation in a murine model of pulmonary fibrosis"
OS13 Sara Manin - University of Catania
"Nanocrystals technology to enhance limitations of isoliquiritigenin"
OS14 Roberta Cillari - University of Palermo
"N,S-doped carbon nanodots conjugated with indoximod for a dual-mode approach in breast cancer immunotherapy"
OS15 Mattia Danilo Langellotto - University of Sassari
"Media milling optimization for rapid extraction of nanovesicles from lemon"
OS16 Elide Zingale - University of Catania
"Self-nanoemulsifying drug delivery systems (SNEDDS) improve curcumin's impact on retinal protection"
OS17 Denise Di Lena - University of Parma
"Single-step monitoring of bioavailable therapeutic antibodies using a protein-DNA nanoswitch platform"
16:10 Coffee break
16:40 Invited talk, IT1
Chairperson: TBD
Rosalia Moreddu - University of Southampton
"Decoding bioelectricity in living systems"
17:10 Session 3, Visualization
Chairperson: TBD
O10 Lorenzo Arrico - University of Pisa
"New Eu(III)-based luminescent probes for time-gating fluorescence microscopy"
O11 Jerneja Kladnik - University of Ljubljana
"Next-generation FDDNP analogues for amyloid β visualization"
O12 Andrea Cesari - University of Pisa
"The role of NMR Spectroscopy for the investigation of nanocarriers in drug delivery applications"
17:50 Session 3S, Light
Chairperson: TBD
OS18 Giuseppina Biscari - University of Palermo
"NIR-responsive antimicrobial hydrogels based on gellan gum and bis-mpa polyester dendrimers"
OS19 Erika Maria Ricci - University of Chieti
"Rapid determination of solar UV filters in human whole blood, plasma and urine using an FPSE-HPLC pda method"
OS20 Michele Catacchio - University of Bari
"Few-Molecule Detection via SPR Enabled by pH Conditioning"
18:20 Social activity, Guided Tour in Palermo (ca. 2 hours)
Tuesday, June 24th
9:00 Session 4, Mechanisms
Chairperson: TBD
O13 Angela Parise - CNR-IOM, SISSA
"Revealing the intricate regulatory mechanisms of small Rho-GTPases"
O14 Stefania Melini - University of Naples Federico II
"Effects of N-acylethanolamines on metabolic damage and cellular stress mechanisms driven by obesity"
O15 Alessia Distefano - University of Catania
"Exploring cellulose nanocrystals as potential nanocarriers for copper ion delivery"
O16 Gabriele Cianfoni - Sapienza University of Rome
"Design and synthesis of linear polyamines for the development of highly performing ferritin-conjugates"
10:00 Session 4s, Cancer
Chairperson: TBD
OS21 Chiara Pastura - University of Catania
"Integrating microfluidics and plasmonics for capturing and detecting alterations in genomic DNA from circulating tumor cells"
OS22 Juliana Manchado - University of Palermo
"The effect of metal ion coordination on the photodynamic activity of chlorins for Photodynamic Therapy"
OS23 Marzia Fois - University of Ljubljana
"Mitochondrial KV1.3 inhibitors: A New Frontier in Anticancer Therapy
OS24 Maria Pia Caputo - University of Bari
"Multivariate quality control and machine learning for early pancreatic cancer diagnosis using the SiMoT platform"
OS25 Davide Ricci - University of Palermo
"New horizons in TP53 nonsense mutations treatment: unveiling novel translational readthrough-inducing drugs for cancer therapy"
OS26 Alessia Marconi - University of Bologna
"Innovative chemophototherapy strategies for cancer"
OS27 Francesco Cancilla - University of Palermo
"Waterborne polyurethane-based electroresponsive platforms for controlled chemotherapy delivery"
OS28 Martina Piga - University of Ljubljana
"Fighting Cancer at the Proton Gate: New HV1 Proton Channel Inhibitors"
OS29 Michele Menditto - University of Palermo
"TRIDs therapy for restoring p53 expression on stop mutated cells"
11:00 Plenary Lecture, PL2
Chairperson: TBD
Andrew deMello - ETH Zürich
"Microfluidics for blood-based diagnostics".
11:50 Session 5, Applications
Chairperson: TBD
O17 Carla Rizzo - University of Palermo
"Fluorinated oxadiazoles as potential scaffolds for biomaterials"
O18 Attilio Marino - Italian Institute of Technology
"Biodegradable organic smart nanoparticles for biomedical applications on earth and beyond"
O19 Neda Bagheri - University of Rome "Tor Vergata"
"Synthetic DNA transducers: enhancing CRISPR-Cas12a applications beyond nucleic acids"
12:35 Session 5S, Applications
Chairperson: TBD
OS30 Serena Vittorio - University of Milan
"Integrating ligand and structure-based approaches to predict UGT-mediated drug metabolism"
OS31 Antonella Miglione - Univerisity of Naples Federico II
"Electrochemical screen-printed sensor for tacrolimus detection in whole blood: a step toward decentralize therapeutic drug monitoring"
OS32 Paola Sofia Cardinale - University of Palermo
"Adipose-derived stem cells and nutrigenomics: a new frontier in obesity treatment"
OS33 Nicole Pia Navatti - Univerisity of Naples Federico II
"Targeting fat-to-heart crosstalk in obesity: preclinical evidence on the effects of N-acylethanolamines mixture"
OS347 Alberto Deplano - University of Cagliari
"Harnessing hSTING for enhanced antiviral response"
OS35 Simona Barone - Univerisity of Naples Federico II
"Discovery of the first-in-class pyrazole-oxazole based synergistic antifungal agent: synergy studies, in silico investigation, and in vivo validation"
OS36 Miriam Cavinato - University of Milan
"PROTACs: a new strategy to target hDASPO degradation for the modulation of endogenous D-aspartate in schizophrenia"
OS37 Marco Banzato - University of Padua
"Synthesis of enantiopure (R)- and (S)-methadone metabolites via a cyclic sulfamidate approach and pharmacological evaluation as novel NMDAR antagonists"
OS38 Sara Mocka - University of Catania
"Synthesis of new 5-fluorouracil and heme oxygenase 1 inhibitor mutual prodrugs with antiproliferative effects"
13:40 Poster session 1, P1 + Lunch + Group photo
14:50 Session 6, Cancer
Chairperson: TBD
O20 Domiziana Masci - Catcholic University of Sacred Heart
"Novel dual-targeting carbonic anhydrase inhibitors: a promising strategy for cancer therapy"
O21 Patrizia Sarogni - Italian Institute of Technology
"Evaluation of rationally designed Topoisomerase inhibitors and FLASH radiotherapy for the treatment of head and neck carcinoma"
O22 Arianna Bonizzi - University of Milan
"A high-sensitivity approach for detection of breast cancer-derived extracellular vesicles using single molecule array technology"
O23 Panagiota Kalligosfyri - University of Naples Federico II
"Fully 3D-printed electrochemical sensor for miRNA detection in liquid biopsy applications"
O24 Giuseppina Santonoceta - University of Catania
"pH-responsive metal-coordinated assemblies for methotrexate delivery in cancer therapy"
16:00 Sponsor talk, ST2
Fabio Perissinotto - Alfatest
"Title TBD"
16.15 Session 6s, RNA-centered
Chairperson: TBD
OS39 Thea Serra - University of Turin
"A novel lateral flow biosensor for the early detection of ovarian cancer-related microRNAs"
OS40 Andrea Deiana - University of Sassari
"Design and synthesis of a new generation of pan-RNA-virus inhibitors"
OS41 Alessandra Glovi - University of Naples Federico II
"Circulating miRNA-21 monitoring in Triple Negative Breast Cancer: a step toward portable liquid biopsy"
OS42 Elisa Schiavon - University of Padua
"siRNA therapeutics and the hurdles of delivery: insights from ANANAS nanoparticles"
OS43 Giulia Yuri Moscatiello - Mario Negri Institute
"Interaction of mRNA-based COVID-19 vaccines with lung adenocarcinoma cells"
16:50 Coffee Break
17:20 Invited talk, IT2
Chairperson: TBD
Laura Fusco - University of Padua
"MXenes from immune interactions to imaging applications"
17:50 Session 7, Natural
Chairperson: TBD
O25 Matteo Perra - University of Cagliari
"Nutriosomes as antioxidant carriers: a comparative study of cannonau grape pomace extract in a parkinson's disease mouse model"
O26 Angela Maione - University of Naples Federico II
"Innovative probiotic-enriched fermented juices: development and functional evaluation"
18:20 Session 7s, Metal-based
Chairperson: TBD
OS44 Sara Benetti - University of Pisa
"Anticancer potential of diiron bis-cyclopentadienyl complexes
OS45 Giorgia Puleo - University of Palermo
"Shaping ZnO synthesis through design of experiments to enhance photocatalysis and antibacterial activity"
OS46 Riccardo Rozza - CNR-IOM, SISSA
"Zinc-aided mechanism of splicing covalent inhibitor"
OS47 Salvatore Muscarella - University of Palermo
"Rationalizing the structural basis of organic-platinum hybrid complexes binding towards quadruplex-duplex hybrids through all-atom simulations"
OS48 Matteo Mari - University of Modena and Reggio Emilia
"Hydrophilic NO3Py derivative for Cu(II) coordination in nuclear medicine"
OS49 Gloria Gatto - University of Verona
"Cuproptosis: a new frontier in targeting PDAC cells"
OS50 Marianna Imparato - University of Naples Federico II
"Effect of a postbiotic-enriched diet on the antioxidant capacity of mytilus galloprovincialis exposed to Cu2O"
20:30 Social dinner + DJ Set
Wednesday, June 25th
9:00 Session 8, Green
Chairperson: TBD
O27 Giulia Di Prima - University of Palermo
"Environmentally friendly strategies to manage oromucosal oxidative stress-related pathologies: from grape processing by-products to polyphenol-rich buccal films"
O28 Chiara Maccari - University of Parma
"Environmental pollution and asthma: exposomic approach"
O29 Andrea Citarella - University of Milan
"Green synthesis and biological evaluation of 1,2,3-triazoles"
O30 Chiara Martino - University of Palermo
"The different effects of two global warming conditions on two sea urchin species exposed to environmental pollutants"
10:00 Session 8s, Scaffolds
Chairperson: TBD
OS51 Rosella Prestia - Polytechnic of Milan
"Rational design of 3D-printed microfluidic columns for integration with chromatographic systems"
OS52 Ignazio Sardo - University of Pisa
"Engineering a high-affinity Fn3 scaffold protein for selective targeting of mesothelin in oncology"
OS53 Angela Pagliaro - University of Cagliari
"Rational design and synthesis of hSTING selective agonists as broad-spectrum antiviral approach"
OS54 Antonietta De Falco - University of Naples Federico II
"From repositioning to drug development: design and synthesis of novel captopril-inspired mbl inhibitors"
OS55 Mariya Ryzhuk - Sapienza University of Rome
"Aromatic abietane diterpenoids as a promising scaffold for the development of Arnt-mediated colistin resistance inhibitors"
OS56 Francesco La Monica - University of Palermo
"Seeding primary fibroblasts and microvascular fragments in plla scaffolds for a regenerative medicine approach"
OS57 Antonella Torre - University of Cagliari
"Computationally driven design of novel hSTING agonists for enhanced antiviral response"
10:50 Plenary Lecture, PL3
Chairperson: TBD
Stefania Butini - University of Siena
"Title TBD"
11:40 Session 9, Biomimetics
Chairperson: TBD
O31 Fabio Pizzetti - Polytechnic of Milan
"Decorated nanogels for modulating glial cells in spinal cord injury"
O32 Jessica Brandi - University of Verona
"Evaluating astaxanthin-loaded nanoparticles as drug delivery systems for ocular diseases: an LC-MS/MS-based investigation"
O33 Laura Di Muzio - Sapienza University of Rome
"Gelatin-based double network cryogels: influence of gelatin properties on mechanical and biological performance in 3D cell culture"
O34 Valentina Testa - University of Turin
"Groundbreaking NanoMIP technology for adenosine detection and integration in antibody-free bioassays"
12:35 Sponsor talk, ST3
TBD - Instron
"Title TBD"
12:45 Session 9s, Sustainable
Chairperson: TBD
OS58 Francesca Terracina - University of Palermo
"Spray-dried soy protein-based microparticles encapsulating Phycocyanin from Spirulina for inflammatory bowel disease treatment: In vivo efficacy evaluation"
OS59 Andrea Capucciati - University of Pavia
"PDA and DHN melanin: an eco-friendly material for removing emerging contaminants from water"
OS60 Francesca Commito - University of L'Aquila
"Encapsulation of saffron in liposomes: formulation, stability, and applications"
OS61 Federica Meringolo - University of Calabria
"Amination of cellulose supports for preparation of antimicrobial materials"
OS62 Asma Munir - University of Bologna
"Sustainable biorefining of rice waste: extraction and utilization of value-added components for biomedical applications"
OS63 Anna Emanuele - University of Florence
"MIP-based sensor for the determination of PFOA in wastewater samples"
13:30 Poster session 3, P3 + Lunch
14:15 Invited talk, IT3
Chairperson: TBD
Alessio Malfanti - University of Padua
"Exploring hyaluronic acid-conjugates for glioblastoma local chemo-immunotherapy"
14:45 Session 10, Structure-activity
Chairperson: TBD
O35 Davide Moi - University of Cagliari
"Tuning the dual HDAC6/Hsp90 inhibition by purine-based hydroxamic acids"
O36 Raffaele Pastore - University of Molise
"Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dys-homeostasis"
O37 Paola Marzullo - University of Palermo
"Structure-activity relationship study of quaternary ammonium salts: synthesis, characterization, and antibacterial evaluation"
15:30 Session 10s, Nucleic acids
Chairperson: TBD
OS64 Ankita Sinha - University of Rome Tor Vergata
"DNA repair monitoring through an electrochemical scaffold sensor"
OS65 Sara Volpes - University of Palermo
"Aphanizomenon flos-aquae (AFA), a new potential therapeutic microalgae against aberrant DNA methylation and DNA damage"
OS66 Marta Marchesini - Polytechnic of Milan
"Optimizing hybridization temperature in nucleic acid-based point-of-care diagnostics"
OS67 Serena Gargano - University of Palermo
"DNA hypomethylation compromises chromosomal stability and drives defects in cell nucleus structure and mechanics"
OS68 Salvatore Martino - University of Palermo
"DNA methylation loss leads to failure in chromosome segregation faithfulness
16:00 Coffee break
16:20 Closing Remarks + Awards
List of poster contributions
Poster Session 1, P1
1: Emanuele Vitale - University of Palermo
"Targeting Nonsense Mutations: NV848, NV914, and NV930 for REP1 protein restoration in Choroideremia"
2: Asya Zerbato - University of Padua
"Peptides functionalized metal nanoparticles for dynamic cell interaction"
3: Dario Savoca - University of Palermo
"Does environmental warming enhance the toxic effects of phthalates on marine life?"
4: Antonio Bova - University of Pavia
"A novel chemometric strategy for in-situ electrical conductivity prediction of tap water in a flow system"
5: Vincenzo Piscopo - University of Palermo
"Design of ZnO nanostructures for the electrochemical sensing of creatinine in aqueous solution"
6: Margherita Massironi - Mario Negri Institute
"The effect of the temperature on the interaction between SLNPs loading a mRNA and target cells"
7: Atieh Mousavi - University College Cork
"Enabling early detection of ovarian cancer using a novel electrochemical sensing platform"
8: Francesca Bertini - Sapienza University of Rome
"Evaluation of the biocidal activity of Origanum vulgare L. essential oil in nanoemulsion"
9: Alessia Lo Re - University of Palermo
"Nanocomposite in situ forming hyaluronic acid hydrogels as potential bone filler for the regeneration of irregular bone defects"
10: Haidi Shehi -University of Milan
"Noncompetitive α amylase and α glucosidase inhibitors for type 2 diabetes treatment"
11: Giulia Maria Titone - University of Palermo
"Targeting the FLT3 receptor in AML therapy with Pharmacophore-Based Virtual Screening: An in silico approach to discovering new potential inhibitors"
Poster session 2, P2
12: Martina Stocco - University of Padua
"Platforms for therapeutic RNA/DNA delivery: Fusogenic ANANAS-based system for targeted delivery of siRNA/miRNA"
13: Riccardo Varrica -University of Palermo
"Antisense oligonucleotides as a therapeutic strategy in rare genetic diseases: applications in hutchinson-gilford progeria syndrome and duchenne muscular dystrophy"
14: Mayla Metitiero - Institut de Ciència de Materials de Barcelona
"Electrolyte-gated organic transistors for electrically monitoring the aggregation of oligoglycine tectomers"
15: Valentina Preziosi - University of Naples Federico II
"Assessing biomarkers in biological fluids by combining microfluidics and organic electrochemical transistors"
16: Armando Gisonna - University of Naples Federico II
"Celecoxib activates a ROS-mediated mitochondrial apoptotic program in 2D and 3D melanoma cell cultures"
17: Flavia Borrelli -Polytechnic of Milan
"Molecular dynamics-guided design of self-assembling antimicrobial peptides"
18: Lucia Abbatiello - University of Sannio
"Rational design and synthesis of novel alkylamides based on natural leads from zanthoxylum spp. and acmella oleracea and evaluation of their biological activity"
19: Alessia Berbiglia - University of Messina
"Selection and characterization of human single-chain antibody fragments capable of recognizing therapeutic anti-sense oligonucleotides bearing phosphorothioate backbones"
20: Anita Salmaso - Mario Negri Institute
"Nanoparticles for pulmonary drug delivery: MALDI-TOF analysis of imatinib-loaded liposomes after intranasal administration in a murine model of pulmonary fibrosis"
21: Alessandra Lipani - University of Palermo
"Identification of new small molecules as F508del-CFTR correctors for the treatment of cystic fibrosis"
22: Maria Luisa Perina - University of Catania
"Albumin conformational changes due to oxidation processes: a systematic approach"
Poster session 3, P3
23: Stefania Carbone - University of Naples Federico II
"Pyro-electrohydrodynamic approach for a high-sensitive and efficient jet printing of biomolecules"
24: Despoina Maria Varouchaki - Sapienza University of Rome
"Ferritin-polyamine conjugates for targeted delivery of siRNA therapeutics"
25: Guglielmo Emanuele Franceschi - University of Pavia
"Development of a chemo-assisted optical device for serum albumin sensing"
26: Gabriella Iula -University of Naples Federico II
"Electrochemical sensor to evaluate cellular toxicity through the analysis of nitrite ions"
27: Raj Paul- University of Rome
"DNA condensates as a platform for biosensing and therapeutic delivery"
28: Marta Cabibbo - University of Palermo
"Addressing the need for pulmonary siRNA delivery with polyaspartamide-based polyplexes"
29: Francesco Cairone - Sapienza University of Rome
"Kaki as natural anti-biofilm agent: strategies to control biofilm-forming candida"
30: Leonardo Brunetti -University of Bari
"An exploration of FPR2 signaling bias by ureidopropanamide derivatives"
31: Valentina Frusca -Scuola Superiore Sant' Anna
"Selenium nano-architectures selectively inhibit cell viability in vitro in hpv-negative oral carcinoma"
32: Angelica Fusi - University of Bologna
"Luminescent nanomaterial-enhanced immunosensing for personalized prostate cancer biomarker analysis"
33: Jelle Verdonck - KU Leuven
"Unravelling the epigenetic mechanisms underlying the occupational carcinogenesis of hexavalent chromium"
34: Mariia Savchenko- King's College London
"Magnetite mineralization inside cross-linked protein crystals"